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Anti-Collagen I/III polyclonal antibody

Cat no: DPABY-040

Anti-Collagen I/III polyclonal antibody

Rabbit anti-Pig Collagen I/III polyclonal antibody for IHC-Fr, ELISA, IF. Defects in COL1A1 are the cause of Caffey disease (CAFFD) [MIM:114000]; also known as infantile cortical hyperostosis. Caffey disease is characterized by an infantile episode of massive subperiosteal new bone formation that typically involves the diaphyses of the long bones, mandible, and clavicles. The involved bones may also appear inflamed, with painful swelling and systemic fever often accompanying the illness. The bone changes usually begin before 5 months of age and resolve before 2 years of age. Defects in COL3A1 are a cause of Ehlers-Danlos syndrome type 3 (EDS3) [MIM:130020]; also known as benign hypermobility syndrome. EDS is a connective tissue disorder characterized by hyperextensible skin, atrophic cutaneous scars due to tissue fragility and joint hyperlaxity. EDS3 is a form of Ehlers-Danlos syndrome characterized by marked joint hyperextensibility without skeletal deformity.

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SPECIFICATIONS

Catalog Number

DPABY-040

Applications

ELISA

Hosts

Rabbit

Conjugates

Unconj

Target

COL4

Isotype

IgG

Clonality

Polyclonal

Storage Temp

Prior to reconstitution store at +4В°C.After reconstitution store at -20В°C.Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody.

SUPPLIER INFO

Creative Diagnostics

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