Rabbit Anti-Human COQ3 polyclonal antibody for WB, ELISA. Ubiquinone, also known as coenzyme Q, or Q, is a critical component of the electron transport pathways of both;eukaryotes and prokaryotes (Jonassen and Clarke, 2000 (PubMed 10777520)). This lipid consists of a hydrophobic;isoprenoid tail and a quinone head group. The tail varies in length depending on the organism, but its purpose is to;anchor coenzyme Q to the membrane. The quinone head group is responsible for the activity of coenzyme Q in the;respiratory chain. The S. cerevisiae COQ3 gene encodes an O-methyltransferase required for 2 steps in the biosynthetic;pathway of coenzyme Q. This enzyme methylates an early coenzyme Q intermediate, 3,4-dihydroxy-5-polyprenylbenzoic;acid, as well as the final intermediate in the pathway, converting demethyl-ubiquinone to coenzyme Q. The COQ3 gene;product is also capable of methylating the distinct prokaryotic early intermediate 2-hydroxy-6-polyprenyl;phenol.
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