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Anti-CREB (phospho S133) polyclonal antibody [Alexa Fluor® 647]

Cat no: CABT-B1858

Anti-CREB (phospho S133) polyclonal antibody [Alexa Fluor® 647]

Rabbit Anti-CREB polyclonal antibody for IF. Cyclic AMP-responsive element-binding protein 1 (UniProt P16220; also known as cAMP-responsive element-binding protein 1, CREB-1) is encoded by the CREB1 gene (Gene ID 1385) in human. CREB is a transcription factor that binds the cAMP response elements (CRE) and regulates the transcription of the downstream genes. CREB activity is regulation via phosphorylation by various kinases, including PKA, and Ca2+/calmodulin-dependent protein kinases. Genes known to be regulated by CREB include c-fos, BDNF, tyrosine hydroxylase, neuropeptides (such as somatostatin, enkephalin, VGF, and corticotropin-releasing hormone), as well as the circadian clock genes PER1 and PER2. CREB is critical for memory formation across a wide range of species.

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SPECIFICATIONS

Catalog Number

CABT-B1858

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Target

CREB1

Gene Id

1385

Isotype

IgG1

Clonality

Polyclonal

Storage Temp

Stable for 1 year at 2-8В°C from date of receipt.

SUPPLIER INFO

Creative Diagnostics

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