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Anti-CST3 (aa 1-100) polyclonal antibody

Cat no: CABT-BL1156

Anti-CST3 (aa 1-100) polyclonal antibody

Rabbit Anti-Human CST3 polyclonal antibody for ICC/IF, IHC-P, WB. Cystatin C or cystatin 3 (formerly gamma trace, post-gamma-globulin or neuroendocrine basic polypeptide), a protein encoded by the CST3 gene, is mainly used as a biomarker of kidney function. Recently, it has been studied for its role in predicting new-onset or deteriorating cardiovascular disease. It also seems to play a role in brain disorders involving amyloid (a specific type of protein deposition), such as Alzheimer's disease. In humans, all cells with a nucleus (cell core containing the DNA) produce cystatin C as a chain of 120 amino acids. It is found in virtually all tissues and body fluids. It is a potent inhibitor of lysosomal proteinases (enzymes from a special subunit of the cell that break down proteins) and probably one of the most important extracellular inhibitors of cysteine proteases (it prevents the breakdown of proteins outside the cell by a specific type of protein degrading enzymes). Cystatin C belongs to the type 2 cystatin gene family.

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SPECIFICATIONS

Catalog Number

CABT-BL1156

Hosts

Rabbit

Reactivities

Hum

Conjugates

Unconj

Target

Cystatin C

Gene Id

1471

Isotype

IgG

Clonality

Polyclonal

Storage Temp

Store at +4В°C short term (1-2 weeks). Aliquot and store at -20В°C or -80В°C. Avoid repeated freeze / thaw cycles.

SUPPLIER INFO

Creative Diagnostics

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