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Anti-Cyclin D1 monoclonal antibody, clone SN352

Cat no: CABT-BL8525

Anti-Cyclin D1 monoclonal antibody, clone SN352

Rabbit Anti-Human Cyclin D1 monoclonal antibody for IHC,WB. The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis. [provided by RefSeq, Jul 2008]

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SPECIFICATIONS

Catalog Number

CABT-BL8525

Hosts

Rabbit

Reactivities

Hum, Mouse

Clone

SN352

Target

CCND1

Gene Id

595

Isotype

IgG

Clonality

Monoclonal

Storage Temp

Stable for 1 Year at -20.0В°C from date of receipt

SUPPLIER INFO

Creative Diagnostics

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