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Anti-CYP3A5 monoclonal antibody, clone FQS5407

Cat no: CABT-BL1192

Anti-CYP3A5 monoclonal antibody, clone FQS5407

Rabbit Anti-Human CYP3A5 monoclonal antibody for ICC, IHC-P, IP, WB. This gene,CYP3A5, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. The enzyme metabolizes drugs such as nifedipine and cyclosporine as well as the steroid hormones testosterone, progesterone and androstenedione. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. This cluster includes a pseudogene, CYP3A5P1, which is very similar to CYP3A5. This similarity has caused some difficulty in determining whether cloned sequences represent the gene or the pseudogene. Multiple alternatively spliced transcript variants have been identified for this gene.

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SPECIFICATIONS

Catalog Number

CABT-BL1192

Hosts

Rabbit

Reactivities

Hum

Conjugates

Unconj

Clone

FQS5407

Target

CYP3A5

Gene Id

1577

Isotype

IgG1

Clonality

Monoclonal

Storage Temp

Store at -20В°C. Stable for 12 months at -20В°C

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