Anti-Cytokeratin Pan monoclonal antibody, clone Mv6

Mouse anti-Cytokeratin Pan monoclonal antibody for IHC. Cytokeratins, a group comprising at least 29 different proteins, are characteristic of epithelial and trichocytic cells. Cytokeratins 1, 4, 5, 6, and 8 are members of the type II neutral to basic subfamily. Monoclonal anti cytokeratins are specific markers of epithelial cell differentiation and have been widely used as tools in tumor identification and classification. Monoclonal Anti Pan Cytokeratin (mixture) is a broadly reactive reagent, which recognizes epitopes present in most human epithelial tissues. It facilitates typing of normal, metaplastic and neoplastic cells. Synergy between the various components results in staining amplification. This enables identification of cells, which would otherwise be stained only marginally. The mixture may aid in the discrimination of carcinomas and nonepithelial tumors such as sarcomas, lymphomas and neural tumors. It is also useful in detecting micrometastases in lymph nodes, bone marrow and other tissues and for determining the origin of poorly differentiated tumors. There are two types of cytokeratins the acidic type I cytokeratins and the basic or neutral type II cytokeratins. Cytokeratins are usually found in pairs comprising a type I cytokeratin and a type II cytokeratin. Usually the type II cytokeratins are 8kD larger than their type I counterparts.

Prices direct from Creative Diagnostics

Quick response times

Exclusive Biosave savings/discounts

SPECIFICATIONS

Catalog Number

DMABT-H21698

Hosts

Mouse

Conjugates

Unconj

Clone

Mv6

Target

Cytokeratin Pan

Isotype

IgG1

Clonality

Monoclonal

Storage Temp

The lyophilized antibody is stabe when stored at 2-8 В°C.The reconstituted antibody solution is stable at 2-8 В°C for three monthes. The solution can be stored in aliquots at -15 to -25 В°C for 12 monthes. Avoid repeat freeze/thaw cycles.