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Anti-DHCR7 (aa 1-259) polyclonal antibody

Cat no: CABT-BL4505

Anti-DHCR7 (aa 1-259) polyclonal antibody

Rabbit Anti-Human DHCR7 (aa 1-259) polyclonal antibody for WB. This gene encodes an enzyme that removes the C(7-8) double bond in the B ring of sterols and catalyzes the conversion of 7-dehydrocholesterol to cholesterol. This gene is ubiquitously expressed and its transmembrane protein localizes to the endoplasmic reticulum membrane and nuclear outer membrane. Mutations in this gene cause Smith-Lemli-Opitz syndrome (SLOS); a syndrome that is metabolically characterized by reduced serum cholesterol levels and elevated serum 7-dehydrocholesterol levels and phenotypically characterized by mental retardation, facial dysmorphism, syndactyly of second and third toes, and holoprosencephaly in severe cases to minimal physical abnormalities and near-normal intelligence in mild cases. Alternative splicing results in multiple transcript variants that encode the same protein.[provided by RefSeq, Aug 2009]

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SPECIFICATIONS

Catalog Number

CABT-BL4505

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Conjugates

Unconj

Target

DHCR7

Gene Id

1717

Isotype

IgG

Clonality

Polyclonal

Storage Temp

Shipped at 4В°C. Upon delivery aliquot and store at -20В°C or -80В°C. Avoid repeated freeze/thaw cycles.

SUPPLIER INFO

Creative Diagnostics

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