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Anti-dimethyl Histone H3 (Lys4) polyclonal antibody [Alexa Fluor® 555]

Cat no: CABT-B1684

Anti-dimethyl Histone H3 (Lys4) polyclonal antibody [Alexa Fluor® 555]

Rabbit Anti-Human dimethyl Histone H3 polyclonal antibody for ICC. Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the beads on a string structure. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine. Histone H3 variants (H3.1, H3.2 and H3.3) have been implicated in the epigenetic memory of cellular state. Genome-wide patterns of H3 are dependent on amino acid sequence and change with cellular differentiation at developmentally regulated loci.

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SPECIFICATIONS

Catalog Number

CABT-B1684

Hosts

Rabbit

Reactivities

Hum

Target

HIST1H3A

Gene Id

8290

Clonality

Polyclonal

Storage Temp

Stable for 1 year at 2-8В°C from date of receipt.

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SUPPLIER INFO

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