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Anti-DL-5-hydroxytryptophan monoclonal antibody, clone D96H98

Cat no: DMAB8635


Supplier: Creative Diagnostics
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Mouse anti-DL-5-hydroxytryptophan monoclonal antibody for IHC, ICC, ELISA, WB. Serotonin (5-hydroxytryptamine, or 5-HT) is a monoamine neurotransmitter synthesised in serotonergic neurons in the central nervous system and enterochromaffin cells in the gastrointestinal tract. Serotonin plays an important part in the biochemistry of depression, migraine, bipolar disorder and anxiety. It is also believed to be influential on sexuality and appetite. 5-HT is generally thought not to be released from synaptic terminal buttons in the manner of classical neurotransmission but from serotonergic varacosities into the extra neuronal space. From here it is free to diffuse over a relatively large region of space ( 20µm) and activate 5-HT receptors located on the dendrites, cell bodies and presynaptic terminals of adjacent neurons. Serotonergic action is terminated primarily via uptake of 5-HT from the synapse. This is through the specific monoamine transporter for 5-HT, 5-HT reuptake transporter, on the presynaptic neuron. The pharmacology of 5-HT is extremely complex, with its actions being mediated by a large and diverse range of 5-HT receptors.
Catalogue number: DMAB8635
Hosts: Mouse
Applications: ELISA
Conjugates: Unconjugated
Clone: D96H98
Target: Tryptophan
Isotype: IgG1
Clonality: Monoclonal
Storage temp: Store the antibody at 4°C for one month or -20°C in undiluted aliquots for up to one year. Avoid repeated freezing and thawing. Gently spin down material before use; 5-10 seconds in a microfuge should be adequate.

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