Anti-DL-5-hydroxytryptophan monoclonal antibody, clone D96H98

Mouse anti-DL-5-hydroxytryptophan monoclonal antibody for IHC, ICC, ELISA, WB. Serotonin (5-hydroxytryptamine, or 5-HT) is a monoamine neurotransmitter synthesised in serotonergic neurons in the central nervous system and enterochromaffin cells in the gastrointestinal tract. Serotonin plays an important part in the biochemistry of depression, migraine, bipolar disorder and anxiety. It is also believed to be influential on sexuality and appetite. 5-HT is generally thought not to be released from synaptic terminal buttons in the manner of classical neurotransmission but from serotonergic varacosities into the extra neuronal space. From here it is free to diffuse over a relatively large region of space ( 20µm) and activate 5-HT receptors located on the dendrites, cell bodies and presynaptic terminals of adjacent neurons. Serotonergic action is terminated primarily via uptake of 5-HT from the synapse. This is through the specific monoamine transporter for 5-HT, 5-HT reuptake transporter, on the presynaptic neuron. The pharmacology of 5-HT is extremely complex, with its actions being mediated by a large and diverse range of 5-HT receptors.

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SPECIFICATIONS

Catalog Number

DMAB8635

Applications

ELISA

Hosts

Mouse

Conjugates

Unconj

Clone

D96H98

Target

Tryptophan

Isotype

IgG1

Clonality

Monoclonal

Storage Temp

Store the antibody at 4В°C for one month or -20В°C in undiluted aliquots for up to one year. Avoid repeated freezing and thawing. Gently spin down material before use; 5-10 seconds in a microfuge should be adequate.