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Anti-DMPO Nitrone Adduct monoclonal antibody, clone M1665B

Cat no: DMAB8088


Supplier: Creative Diagnostics
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Mouse anti-DMPO Nitrone Adduct monoclonal antibody for ICC/IHC, IF. The formation of free radicals and other highly reactive oxygen species has been implicated in the pathogenesis of many disease states. The ability to identify these species is crucial, and spin trapping has accomplished this goal. DMPO (5,5-dimethyl-1-pyrroline N-oxide) is one of the least toxic to cells and animals, and possesses convenient pharmacokinetics (uptake, distribution, metabolism and excretion) in biological systems. Recent studies have determined that nitric oxide may substantially affect the quantitative determination of DMPO adducts, and therefore extra caution is required when studying generation of these species in the presence of nitric oxide or its radicals. DMPO adducts can be generated with protein and DNA radicals.
Catalogue number: DMAB8088
Hosts: Mouse
Conjugates: Unconjugated
Clone: M1665B
Target: DMPO
Isotype: IgG1
Clonality: Monoclonal
Storage temp: -20°C; 1 year+; shipped on cold packs or ambient

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