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Anti-DMPO Nitrone Adduct monoclonal antibody, clone M1665B

Cat no: DMAB8088

Anti-DMPO Nitrone Adduct monoclonal antibody, clone M1665B

Mouse anti-DMPO Nitrone Adduct monoclonal antibody for ICC/IHC, IF. The formation of free radicals and other highly reactive oxygen species has been implicated in the pathogenesis of many disease states. The ability to identify these species is crucial, and spin trapping has accomplished this goal. DMPO (5,5-dimethyl-1-pyrroline N-oxide) is one of the least toxic to cells and animals, and possesses convenient pharmacokinetics (uptake, distribution, metabolism and excretion) in biological systems. Recent studies have determined that nitric oxide may substantially affect the quantitative determination of DMPO adducts, and therefore extra caution is required when studying generation of these species in the presence of nitric oxide or its radicals. DMPO adducts can be generated with protein and DNA radicals.

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SPECIFICATIONS

Catalog Number

DMAB8088

Hosts

Mouse

Conjugates

Unconj

Clone

M1665B

Target

DMPO

Isotype

IgG1

Clonality

Monoclonal

Storage Temp

-20В°C; 1 year+; shipped on cold packs or ambient

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