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Anti-DSP monoclonal antibody, clone FQS5494

Anti-DSP monoclonal antibody, clone FQS5494

Cat no: CABT-BL1318

Supplier: Creative Diagnostics
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Rabbit Anti-Human DSP monoclonal antibody for ICC/IF, WB. Desmosomes are intercellular junctions that tightly link adjacent cells. Desmoplakin is an obligate component of functional desmosomes that anchors intermediate filaments to desmosomal plaques. The N-terminus of desmoplakin is required for localization to the desmosome and interacts with the N-terminal region of plakophilin 1 and plakoglobin. The C-terminus of desmoplakin binds with intermediate filaments. In the mid-region of desmoplakin, a coiled-coiled rod domain is responsible for homodimerization. Mutations in this gene are the cause of several cardiomyopathies and keratodermas as well as the autoimmune disease paraneoplastic pemphigus. [provided by RefSeq, Jul 2008]
Catalogue number: CABT-BL1318
Reactivities: Human, Rat
Hosts: Rabbit
Conjugates: Unconjugated
Clone: FQS5494
Gene: 1832
Target: desmoplakin
Isotype: IgG1
Clonality: Monoclonal
Storage temp: Store at -20°C. Stable for 12 months at -20°C

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