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Anti-DSP monoclonal antibody, clone FQS5494

Cat no: CABT-BL1318

Anti-DSP monoclonal antibody, clone FQS5494

Rabbit Anti-Human DSP monoclonal antibody for ICC/IF, WB. Desmosomes are intercellular junctions that tightly link adjacent cells. Desmoplakin is an obligate component of functional desmosomes that anchors intermediate filaments to desmosomal plaques. The N-terminus of desmoplakin is required for localization to the desmosome and interacts with the N-terminal region of plakophilin 1 and plakoglobin. The C-terminus of desmoplakin binds with intermediate filaments. In the mid-region of desmoplakin, a coiled-coiled rod domain is responsible for homodimerization. Mutations in this gene are the cause of several cardiomyopathies and keratodermas as well as the autoimmune disease paraneoplastic pemphigus. [provided by RefSeq, Jul 2008]

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SPECIFICATIONS

Catalog Number

CABT-BL1318

Hosts

Rabbit

Reactivities

Hum, Rat

Conjugates

Unconj

Clone

FQS5494

Target

desmoplakin

Gene Id

1832

Isotype

IgG1

Clonality

Monoclonal

Storage Temp

Store at -20В°C. Stable for 12 months at -20В°C

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