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Anti-DSP polyclonal antibody

Anti-DSP polyclonal antibody

Cat no: CABT-BL1319

Supplier: Creative Diagnostics
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Rabbit Anti-Human DSP polyclonal antibody for WB. Desmosomes are intercellular junctions that tightly link adjacent cells. Desmoplakin is an obligate component of functional desmosomes that anchors intermediate filaments to desmosomal plaques. The N-terminus of desmoplakin is required for localization to the desmosome and interacts with the N-terminal region of plakophilin 1 and plakoglobin. The C-terminus of desmoplakin binds with intermediate filaments. In the mid-region of desmoplakin, a coiled-coiled rod domain is responsible for homodimerization. Mutations in this gene are the cause of several cardiomyopathies and keratodermas as well as the autoimmune disease paraneoplastic pemphigus. [provided by RefSeq, Jul 2008]
Catalogue number: CABT-BL1319
Reactivities: Human
Hosts: Rabbit
Conjugates: Unconjugated
Gene: 1832
Target: desmoplakin
Isotype: IgG
Clonality: Polyclonal
Storage temp: Store at 4°C. Aliquot and store at -20°C long-term.

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