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Anti-Electric EEL Acetylcholinesterase polyclonal antibody

Anti-Electric EEL Acetylcholinesterase polyclonal antibody

Cat no: DPBT-66693RE

Supplier: Creative Diagnostics
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Rabbit anti-Electrophorus electricus Electric EEL Acetylcholinesterase polyclonal antibody for ELISA, WB. Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. It is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. It is encoded by the single ACHE gene, and the structural diversity in the gene products arises from alternative mRNA splicing, and post-translational associations of catalytic and structural subunits. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits. The other, alternatively spliced form, expressed primarily in the erythroid tissues, differs at the C-terminal end, and contains a cleavable hydrophobic peptide with a GPI-anchor site. It associates with the membranes through the phosphoinositide (PI) moieties added post-translationally.
Catalogue number: DPBT-66693RE
Reactivities: Human
Hosts: Rabbit
Applications: ELISA
Conjugates: Unconjugated
Target: ACHE
Isotype: IgG
Clonality: Polyclonal
Storage temp: Store at +4 oC or at -20 oC if preferred.Storage in frost-free freezers is not recommended.This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

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