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Anti-ESR2 (aa 211-240) polyclonal antibody

Anti-ESR2 (aa 211-240) polyclonal antibody

Cat no: CABT-B8910

Supplier: Creative Diagnostics
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Rabbit Anti-ESR2 (aa 211-240) polyclonal antibody for WB, ELISA. Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. Isoform beta-cx lacks ligand binding ability and has no or only very low ere binding activity resulting in the loss of ligand-dependent transactivation ability. DNA-binding by ESR1 and ESR2 is rapidly lost at 37 degrees Celsius in the absence of ligand while in the presence of 17 beta-estradiol and 4-hydroxy-tamoxifen loss in DNA-binding at elevated temperature is more gradual.
Catalogue number: CABT-B8910
Reactivities: Human, Mouse
Hosts: Rabbit
Applications: ELISA
Gene: 2100
Target: ESR2
Isotype: IgG
Clonality: Polyclonal
Storage temp: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

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