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Anti-ESR2 (aa 211-240) polyclonal antibody

Cat no: CABT-B8910

Anti-ESR2 (aa 211-240) polyclonal antibody

Rabbit Anti-ESR2 (aa 211-240) polyclonal antibody for WB, ELISA. Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. Isoform beta-cx lacks ligand binding ability and has no or only very low ere binding activity resulting in the loss of ligand-dependent transactivation ability. DNA-binding by ESR1 and ESR2 is rapidly lost at 37 degrees Celsius in the absence of ligand while in the presence of 17 beta-estradiol and 4-hydroxy-tamoxifen loss in DNA-binding at elevated temperature is more gradual.

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SPECIFICATIONS

Catalog Number

CABT-B8910

Applications

ELISA

Hosts

Rabbit

Reactivities

Hum, Mouse

Target

ESR2

Gene Id

2100

Isotype

IgG

Clonality

Polyclonal

Storage Temp

Maintain refrigerated at 2-8В°C for up to 2 weeks. For long term storage store at -20В°C in small aliquots to prevent freeze-thaw cycles.

SUPPLIER INFO

Creative Diagnostics

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