Anti-Estrone Glucuronide (C-terminal) polyclonal antibody

Sheep anti-Estrone Glucuronide (C-terminal) polyclonal antibody for ELISA. Estradiol (E2 or 17beta-estradiol, also oestradiol) is a sex hormone. Estradiol is abbreviated E2 as it has 2 hydroxyl groups in its molecular structure. Estrone has2(E1) and estriol has4(E3). Estradiol is about20times as potent as estrone and about 80 times as potent as estriol in its estrogenic effect. Except during the early follicular phase of the menstrual cycle, its serum levels are somewhat higher than that of estrone during the reproductive years of the human female. Thus it is the predominant estrogen during reproductive years both in terms of absolute serum levels as well as in terms of estrogenic activity. During menopause, estrone is the predominant circulating estrogen and during pregnancy estriol is the predominant circulating estrogen in terms of serum levels. Estradiol is also present in males, being produced as an active metabolic product of testosterone. The serum levels of estradiol in males (14 - 55 pg/mL) are roughly comparable to those of postmenopausal women (

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SPECIFICATIONS

Catalog Number

DPABY-080

Applications

ELISA

Hosts

Sheep

Conjugates

Unconj

Target

Estrone Glucuronide

Isotype

IgG

Clonality

Polyclonal

Storage Temp

Store at +4В°C or at -20В°C if preferred.Storage in frost-free freezers is not recommended.This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.