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Anti-Farnesyl() polyclonal antibody

Cat no: DPABT-H20172


Supplier: Creative Diagnostics
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Rabbit anti-Farnesyl() polyclonal antibody for ELISA, IF. Isoprenylation/methylation is an important posttranslational lipid modification; the covalent addition of a 15 carbon farnesyl or a30carbon geranylgeranyl group to the C terminus of a protein results in a substantial increase in hydrophobicity. All known G proteins are modified in this way, making the pathway of central interest for an understanding of signal transduction. From nematode to human, many eukaryotic proteins are reported to be isoprenylated. Known prenylated proteins include fungal mating factors, nuclear lamins, Ras and Ras related GTP binding proteins (G proteins), and the subunits of trimeric G proteins, protein kinases and at least one viral protein. Prenylation promotes membrane interactions of most of these proteins, which is not surprising given the hydrophobicity of the lipids involved. In addition, prenylation appears to play a major role in several protein protein interactions.
Catalogue number: DPABT-H20172
Hosts: Rabbit
Applications: ELISA
Conjugates: Unconjugated
Target: Farnesyl
Clonality: Polyclonal
Storage temp: Maintain at -20 °C in undiluted aliquots for up to 12 months from date of receipt. Avoid repeated freeze/thaw cycles.

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