Anti-Fibrinogen alpha chain polyclonal antibody

Rabbit Anti-Human Fibrinogen alpha chain polyclonal antibody for WB, IHC, ELISA. FGA is the alpha component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in its gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis.The protein encoded by this gene is the alpha component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in two isoforms which vary in the carboxy-terminus.

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SPECIFICATIONS

Catalog Number

CABT-B8841

Applications

ELISA

Hosts

Rabbit

Reactivities

Hum

Target

FGA

Gene Id

2243

Isotype

IgG

Clonality

Polyclonal

Storage Temp

For short periods of storage (days) store at 4В°C. For longer periods of storage, store FGA antibody at -20В°C. As with any antibody avoid repeat freeze-thaw cycles.