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Anti-Filamentous HA monoclonal antibody, clone IZC 353-02

Anti-Filamentous HA monoclonal antibody, clone IZC 353-02

Cat no: DMAB5779

Supplier: Creative Diagnostics
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Mouse anti-Filamentous HA monoclonal antibody for ELISA, WB, IHC. Filamentous hemagglutinin (FHA) of Bordetella pertussis is a 220 kDa large adhesive surface protein which together with the pertussis toxin (PTx) facilitates attachment of the bacteria to human ciliated cells and macrophages during the course of whooping cough. FHA can recognize and bind the leukocyte-restricted adhesion molecule suggesting that FHA mimics a natural ligand on endothelial cells for this integrin which enables FHA to competitively interfere with CD18-dependent leukocyte migration to the central nervous system. Anti FHA antibodies have been shown to be able to permeabilize the blood-brain barrier.
Catalogue number: DMAB5779
Hosts: Mouse
Applications: ELISA
Conjugates: Unconjugated
Clone: IZC 353-02
Target: FHA
Isotype: IgG1
Clonality: Monoclonal
Storage temp: 2-8°C.

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