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Anti-GCN5 polyclonal antibody

Cat no: CABT-B1567

Anti-GCN5 polyclonal antibody

Rabbit Anti-Human GCN5 polyclonal for IP; ChIP; ChIPseq; WB. Histone acetyltransferase KAT2A (EC 2.3.1.48; UniProt Q92830; also known as General control of amino acid synthesis protein 5-like 2, hGCN5, Histone acetyltransferase GCN5, HsGCN5, Lysine acetyltransferase 2A, STAF97) is encoded by the KAT2A (also known as GCN5, GCN5L2, HGCN5) gene (Gene ID 2648) in human. Histone acetyltransferases (HATs) are transcription co-activators recruited by transcriptional activators to target gene promoters, where they enhance the transcription activity by acetylating lysine residues within the N-terminal regions of histones. KAT2A/KAT2B, MYST (MOZ, Ybf2 (Sas3), Sas2, and Tip60), TAFII250, CREBBP/EP300, and SRC represent the five HAT families. In addtion to functioning as transcription co-activators, KAT2A (GCN5) and KAT2B (PCAF) are also reported to repress IFN?? production and innate antiviral immunity by inhibiting the innate immune signaling kinase TBK1 in the cytoplasm in a HAT?independent and non?transcriptional manner.

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SPECIFICATIONS

Catalog Number

CABT-B1567

Applications

ChIP

Hosts

Rabbit

Reactivities

Hum, Mouse

Target

KAT2A

Gene Id

2648

Clonality

Polyclonal

Storage Temp

Stable for 1 year at 2-8В°C from date of receipt.

SUPPLIER INFO

Creative Diagnostics

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