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Anti-GNPTAB (N-termianl) polyclonal antibody

Cat no: CABT-B632

Anti-GNPTAB (N-termianl) polyclonal antibody

Rabbit Anti-Human GNPTAB polyclonal antibody for WB. This gene encodes two of three subunit types of the membrane-bound enzyme N-acetylglucosamine-1-phosphotransferase, a heterohexameric complex composed of two alpha, two beta, and two gamma subunits. The encoded protein is proteolytically cleaved at the Lys928-Asp929 bond to yield mature alpha and beta polypeptides while the gamma subunits are the product of a distinct gene (GeneID 84572). In the Golgi apparatus, the heterohexameric complex catalyzes the first step in the synthesis of mannose 6-phosphate recognition markers on certain oligosaccharides of newly synthesized lysosomal enzymes. These recognition markers are essential for appropriate trafficking of lysosomal enzymes. Mutations in this gene have been associated with both mucolipidosis II and mucolipidosis IIIA.

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SPECIFICATIONS

Catalog Number

CABT-B632

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat, Bov, Horse, Rabbit

Conjugates

Unconj

Target

GNPTAB

Isotype

IgG

Clonality

polyclonal

Storage Temp

For longer periods of storage, store at -20В°C. Avoid repeat freeze-thaw cycles.

SUPPLIER INFO

Creative Diagnostics

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