Anti-GRASP65 polyclonal antibody

Rabbit Anti-Rat GRASP65 polyclonal antibody for WB, ICC, IP. Golgi reassembly stacking protein of 65 kDa (also called Golgi reassembly and stacking protein 1 or Golgi peripheral membrane protein p65) is encoded by the Grasp65 or Gorasp65 gene in rat (GRASP65, GORASP1, or GOLPH5 gene in human). It is is a Golgi structural protein and mediates cisternae stacking via self-aggregation as well as interactions with other Golgi membrane-docking proteins, such as GM130. GRASP65 dimers are shown to aggregate in vitro and form extensive trans oligomers, which disaggregate upon phosphorylation by cdc2-cyclin B and polo-like kinases, and re-aggregate upon dephosphorylation. Fluorescent imaging studies reveal a dynamic exchange between the membrane-associated and cytosolic GRASP65.

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SPECIFICATIONS

Catalog Number

CABT-B1901

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Target

GORASP1

Clonality

Polyclonal

Storage Temp

Stable for 1 year at -20В°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20В°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.