Rabbit Anti-Rat Growth Related Oncogene polyclonal antibody for WB. Growth Related Oncogene (GRO) /Cytokine-induced neutrophil chemo attractant 1 (CINC-1) was originally purified from media conditioned by IL-1?stimulated rat kidney epithelioid cells (NRK-52E). Amino acid sequence that encodes for rat CINC-1 was identified in 1989 by Watanabe's group at Toyama Medical and Pharmaceutical University. CINC-1 is a member of the alpha (CXC) subfamily of chemokines. Three additional rat CXC chemokines (CINC-2?, CINC-2?, CINC-3/MIP-2) have been identified. The protein sequence of CINC-1 is 63 - 67% identical to that of CINC-2?, CINC-2?, CINC-3/MIP-2. In addition, GRO?, GRO? and GRO? is sharing 68%, 71% and 69%, identity with CINC-1. This has been suggested that CINCs are the rat counterpart of human GROs.
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