Anti-HATH1 (aa 145-250) polyclonal antibody

Cat no: CABT-B8720

Supplier: Creative Diagnostics

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Rabbit Anti-Human HATH1 polyclonal antibody for ELISA, IHC-P, IHC-Fr, IF. The Drosophila atonal gene produces a protein with basic helix loop helix (bHLH) domains that plays an essential role in the development of the Drosophila nervous system. Mammalian atonal homolog 1 (MATH-1) is a helix-loop-helix (HLH) transcription factor that is structurally homologous to the product of the Drosophila proneural gene atonal. MATH-1, so known as Atoh1, Ath1 or HATH-1, is a 351 amino acid protein with an atonal-related basic HLH domain. In mice, expression of MATH-1 takes place by embryonic day 9.5 and initially localizes to the cranial ganglions and the dorsal part of the central nervous system. Prominent expression of MATH-1 is in the dorsal part of the central nervous system but becomes restricted to the external granular layer of the cerebellum by day 18 and is undetectable in the adult nervous system. It is suggested that MATH-1 may play a role in the differentiation of subsets of neural cells by activating E box-dependent transcription.

Catalogue number:	CABT-B8720
Reactivities:	Human, Mouse, Rat
Hosts:	Rabbit
Applications:	ELISA
Conjugates:	Unconjugated
Gene:	11921
Target:	ATOH1
Isotype:	IgG
Clonality:	Polyclonal
Storage temp:	Store at -20°C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of anti

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Anti-HATH1 (aa 145-250) polyclonal antibody

Cat no: CABT-B8720

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