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Anti-IBTK (aa 589-617) polyclonal antibody

Cat no: CABT-BL4895


Supplier: Creative Diagnostics
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Rabbit Anti-Human IBTK (aa 589-617) polyclonal antibody for WB, IHC-P. Bruton tyrosine kinase (BTK) is a protein tyrosine kinase that is expressed in B cells, macrophages, and neutrophils. The protein encoded by this gene binds to BTK and downregulates BTKs kinase activity. In addition, the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription. This gene has a pseudogene on chromosome 18. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014]
Catalogue number: CABT-BL4895
Reactivities: Human
Hosts: Rabbit
Conjugates: Unconjugated
Gene: 25998
Target: IBTK
Isotype: IgG
Clonality: Polyclonal
Storage temp: Store at 4°C (up to 6 months). For long term storage store at -20°C

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