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Anti-ICOS monoclonal antibody, clone D409.5B

Cat no: CABT-B089

Anti-ICOS monoclonal antibody, clone D409.5B

Hamster Anti-Mouse ICOS monoclonal antibody for IP, IHC, FC. Inducible T-cell co-stimulator (ICOS) enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. The protein is essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. It does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. It prevents the apoptosis of pre-activated T-cells, and plays a critical role in CD40-mediated class switching of immunoglobin isotypes.

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SPECIFICATIONS

Catalog Number

CABT-B089

Hosts

Ham

Reactivities

Hum, Mouse, Rat

Clone

D409.5B

Target

ICOS

Gene Id

29851

Clonality

Monoclonal

Storage Temp

-20В°C

SUPPLIER INFO

Creative Diagnostics

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