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Anti-IDUA polyclonal antibody

Cat no: CABT-B8950

Anti-IDUA polyclonal antibody

Sheep Anti-Human IDUA polyclonal antibody for ELISA, WB, IP, ICC. alpha -L-Iduronidase encoded by the IDUA gene is an important enzyme required for the lysosomal degradation of glycosaminoglycans (GAGs). It hydrolyzes the non?reducing terminal alpha -L-iduronic acid residues in GAGs including dermatan sulfate and heparan sulfate. Mutations in IDUA that result in enzymatic deficiency lead to the autosomal recessive disease mucopolysaccharidosis type I (MPS I). MPS I causes progressive cellular, tissue and organ damage, and several clinical studies using enzyme replacement therapy have shown promising benefits. The sequence of human IDUA shares 79% amino acid identity with mouse IDUA.

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SPECIFICATIONS

Catalog Number

CABT-B8950

Applications

ELISA

Hosts

Sheep

Reactivities

Hum

Target

IDUA

Gene Id

3425

Isotype

IgG

Clonality

polyclonal

Storage Temp

12 months from date of receipt, -20 to -70В°C as supplied.<br/>1 month, 2 to 8В°C under sterile conditions after reconstitution.<br/>6 months, -20 to -70В°C under sterile conditions after reconstitution.

SUPPLIER INFO

Creative Diagnostics

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