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Anti-IDUA polyclonal antibody

Anti-IDUA polyclonal antibody

Cat no: CABT-B8950

Supplier: Creative Diagnostics
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Sheep Anti-Human IDUA polyclonal antibody for ELISA, WB, IP, ICC. alpha -L-Iduronidase encoded by the IDUA gene is an important enzyme required for the lysosomal degradation of glycosaminoglycans (GAGs). It hydrolyzes the non?reducing terminal alpha -L-iduronic acid residues in GAGs including dermatan sulfate and heparan sulfate. Mutations in IDUA that result in enzymatic deficiency lead to the autosomal recessive disease mucopolysaccharidosis type I (MPS I). MPS I causes progressive cellular, tissue and organ damage, and several clinical studies using enzyme replacement therapy have shown promising benefits. The sequence of human IDUA shares 79% amino acid identity with mouse IDUA.
Catalogue number: CABT-B8950
Reactivities: Human
Hosts: Sheep
Applications: ELISA
Gene: 3425
Target: IDUA
Isotype: IgG
Clonality: polyclonal
Storage temp: 12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
6 months, -20 to -70°C under sterile conditions after reconstitution.

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