Anti-IgG monoclonal antibody, clone WQN9

Mouse anti-Sheep IgG monoclonal antibody for IHC-Fr, ELISA, FC, IP, WB.. All five immunoglobulin classes share the same basic four polypeptide chain structure of two heavy-chains and two light chains. There are five heavy chain types, and two light-chain types (Kappa and Lambda) both having a molecular weight of 22.5kDa. Any heavy-chain type can associate with either light-chain type, but on any immunoglobulin molecule both light-chains are of the same type. Kappa and Lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of Kappa to Lambda is 70:30 , the vast majority of which is bound to heavy-chain in immunoglobulin. In normal individuals low levels of free light-chain arepresent in serum (kappa, 1.6-15.2 mg/L; Lambda, 0.4-4.2mg/L), with the occurrence of multiple myeloma or other B-cell malignancies these levels can be greatly elevated and can be found at high levels in the urine (Bence-Jones proteins).

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SPECIFICATIONS

Catalog Number

DCABY-786

Applications

ELISA

Hosts

Mouse

Reactivities

Sheep

Clone

WQN9

Target

IgG

Isotype

IgG1

Clonality

Monoclonal

Storage Temp

Store at +4В°C for one month or at -20В°C for longer.This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.