Anti-IgG2b polyclonal antibody [Cy2]

Rabbit anti-Mouse IgG2b polyclonal antibody for IF.. Immunoglobulin class switching (or isotype switching or isotypic commutation or class switch recombination(CSR)) is a biological mechanism that changes a B cell"s production of antibody from one class to another, for example, from an isotype called IgM to an isotype called IgG. During this process, the constant region portion of the antibody heavy chain is changed, but the variable region of the heavy chain stays the same (the terms "constant" and "variable" refer to changes or lack thereof between antibodies that target different epitopes). Since the variable region does not change, class switching does not affect antigen specificity. Instead, the antibody retains affinity for the same antigens, but can interact with different effector molecules.

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SPECIFICATIONS

Catalog Number

DPAB22378

Hosts

Rabbit

Reactivities

Mouse

Target

IgG2b

Isotype

IgG

Clonality

Polyclonal

Storage Temp

Store vial at 4В°C prior to restoration. For extended storage aliquot contents and freeze at -20В°C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for sev