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Anti-IL12RB1 (aa 50-150) polyclonal antibody

Anti-IL12RB1 (aa 50-150) polyclonal antibody

Cat no: CABT-BL1916

Supplier: Creative Diagnostics
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Rabbit Anti-Mouse IL12RB1 polyclonal antibody for WB. The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. Mutations in this gene impair the development of interleukin-17-producing T lymphocytes and result in increased susceptibility to mycobacterial and Salmonella infections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
Catalogue number: CABT-BL1916
Reactivities: Mouse
Hosts: Rabbit
Conjugates: Unconjugated
Gene: 16161
Target: IL12RB1
Isotype: IgG
Clonality: Polyclonal
Storage temp: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

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