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Anti-IL12RB2 (aa 323-665) polyclonal antibody

Anti-IL12RB2 (aa 323-665) polyclonal antibody

Cat no: CABT-BL4917

Supplier: Creative Diagnostics
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Rabbit Anti-Human IL12RB2 (aa 323-665) polyclonal antibody for WB. The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohns disease and leprosy, which is thought to contribute to the inflammatory response and host defense. Several transcript variants encoding different isoforms and non-protein coding transcripts have been found for this gene. [provided by RefSeq, Apr 2012]
Catalogue number: CABT-BL4917
Reactivities: Human
Hosts: Rabbit
Conjugates: Unconjugated
Gene: 3595
Target: IL12RB2
Isotype: IgG
Clonality: Polyclonal
Storage temp: Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles.

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