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Anti-INPP5E (full length) polyclonal antibody

Anti-INPP5E (full length) polyclonal antibody

Cat no: CABT-BL4927

Supplier: Creative Diagnostics
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Mouse Anti-Human INPP5E (full length) polyclonal antibody for WB. The protein encoded by this gene is an inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase. InsP3 5-phosphatases hydrolyze Ins(1,4,5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation. Studies of the mouse counterpart suggest that this protein may hydrolyze phosphatidylinositol 3,4,5-trisphosphate and phosphatidylinositol 3,5-bisphosphate on the cytoplasmic Golgi membrane and thereby regulate Golgi-vesicular trafficking. Mutations in this gene cause Joubert syndrome; a clinically and genetically heterogenous group of disorders characterized by midbrain-hindbrain malformation and various associated ciliopathies that include retinal dystrophy, nephronophthisis, liver fibrosis and polydactyly.[provided by RefSeq, Feb 2011]
Catalogue number: CABT-BL4927
Reactivities: Human
Hosts: Mouse
Conjugates: Unconjugated
Gene: 56623
Target: INPP5E
Isotype: IgG
Clonality: Polyclonal
Storage temp: Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles.

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