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Anti-Integrin Alpha V + Beta 6 polyclonal antibody [FITC]

Anti-Integrin Alpha V + Beta 6 polyclonal antibody [FITC]

Cat no: CABT-B8553

Supplier: Creative Diagnostics
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Rabbit Anti-Human Integrin Alpha V + Beta 6 polyclonal antibody for IF, FC. Integrins are heterodimeric cell surface receptors composed of alpha and beta subunits, which mediate cell-cell and cell-extracellular matrix attachments. Aberrant integrin expression has been found in many epithelial tumours. Changes in integrin expression have been shown to be important for the growth and early metastatic capacity of melanoma cells. Integrin alpha-v beta-6 is upregulated in cancers and during tissue remodelling but is absent from resting adult tissues. Integrin alpha-v beta-6 promotes invasion and correlates with poor survival and therefore makes a promising therapeutic target.
Catalogue number: CABT-B8553
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Target: Integrin alpha V + beta 6
Isotype: IgG
Clonality: Polyclonal
Storage temp: Store at -20°C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4°C.

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