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anti-Interleukin 17A (IL17A) antibody (Biotin)

Cat no: ABIN964797

anti-Interleukin 17A (IL17A) antibody (Biotin)

anti-Interleukin 17A (IL17A) antibody (Biotin): Rat IL17-A (also known as Interleukin-17, Cytotoxic T-lymphocyte-associated antigen 8 and CTLA-8) is a proinflammatory cytokine member of a six-species family of proteins (IL-17A-17F). Rat IL-17A protein is a homodimer consisting of two 134 amino acids peptides. IL-17A is secreted mainly by activated CD4+ and CD8+ T lymphocytes and acts through its receptor, IL-17R, to induce the expression of many mediators of inflammation, most strikingly, those that are involved in the proliferation, maturation and chemotaxis of neutrophils. Elevated levels of IL-17A have been associated with several conditions, including rheumatoid arthritis, airway inflammation, allograft rejection, inflammatory bowel disease, psoriasis, cancer and multiple sclerosis. There is 58% identity between the amino acid sequence of human and rat IL-17A. Anti-IL-17A antibody is ideal for investigators involved in Immunology research.

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SPECIFICATIONS

Catalog Number

ABIN964797

Size

100 micro g

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Mouse, Rat

Conjugates

Biotin

Antigen

IL-17A

Gene Id

16171,301289

Isotype

IgG

Clonality

Polyclonal

Concentration

1.0 mg/mL

Entrez Gene Id

16171,301289

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