Mouse anti-L-Dihydroxyphenylalanine monoclonal antibody for ELISA, ICC, IHC, WB. L Dopa is an intermediate in dopamine biosynthesis. Clinically, L Dopa is used in the management of Parkinson"s disease. It is used as a prodrug to increase dopamine levels since it is able to cross the blood-brain barrier whereas dopamine itself cannot. Once L Dopa has entered the central nervous system (CNS), it is metabolised to dopamine by aromatic L amino acid decarboxylase. This also occurs in the peripheral tissues, causing adverse effects and decreasing the available dopamine to the CNS, so it is standard practice to co administer a peripheral DOPA decarboxylase inhibitor and often a catechol-O-methyl transferase (COMT) inhibitor.