Anti-Lac I (full length) polyclonal antibody

Rabbit anti-Lac I (full length) polyclonal antibody for WB, ELISA. The lac repressor protein (Lac I) is an important genetic control protein. It controls the expression of the lactose metabolizing enzymes in Escherichia coli. This regulation involves specific recognition of the operator DNA sequence (Lac O) and consequent inhibition of transcription initiation by RNA polymerase; modulation of binding at this target site by small sugar molecules, inducers, provides the basis for regulation. Different ligand binding activities are associated with the isolated domains of Lac I: specific and nonspecific DNA binding with the NH2 termini, and inducer and specific DNA binding with the core protein. This antibody could possibly be used to recover and purify protein/nucleic acid complexes (host and viral proteins associated with the viral DNA) from infected cells.

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SPECIFICATIONS

Catalog Number

DPAB22229

Applications

ELISA

Hosts

Rabbit

Conjugates

Unconj

Target

Lac I

Isotype

IgG

Clonality

Polyclonal

Storage Temp

Store vial at -20В°C prior to opening. Aliquot contents and freeze at -20В°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for sever