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Anti-LECT1 (C-terminal) polyclonal antibody

Cat no: CABT-BL5039

Anti-LECT1 (C-terminal) polyclonal antibody

Rabbit Anti-Human LECT1 (C-terminal) polyclonal antibody for IHC-P, ELISA, WB. This gene encodes a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. The N-terminus of the precursor protein shares characteristics with other surfactant proteins and is sometimes called chondrosurfactant protein although no biological activity has yet been defined for it. The C-terminus of the precursor protein contains a 25 kDa mature protein called leukocyte cell-derived chemotaxin-1 or chondromodulin-1. The mature protein promotes chondrocyte growth and inhibits angiogenesis. This gene is expressed in the avascular zone of prehypertrophic cartilage and its expression decreases during chondrocyte hypertrophy and vascular invasion. The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascularized and replaced by bone. It may be involved also in the broad control of tissue vascularization during development. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

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SPECIFICATIONS

Catalog Number

CABT-BL5039

Applications

ELISA

Hosts

Rabbit

Reactivities

Hum

Conjugates

Unconj

Target

LECT1

Gene Id

11061

Isotype

IgG

Clonality

Polyclonal

Storage Temp

Shipped at 4В°C. Upon delivery aliquot and store at -20В°C or -80В°C. Avoid repeated freeze/thaw cycles.

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