Anti-Macrophages monoclonal antibody, clone NBD498 [R-PE]

Mouse anti-Human Macrophages monoclonal antibody for FC. Macrophages are cells produced by the differentiation of monocytes in tissues. Human macrophages are about 21 micrometres (0.00083 in) in diameter. Monocytes and macrophages are phagocytes. Macrophages function in both non-specific defense (innate immunity) as well as help initiate specific defense mechanisms (adaptive immunity) of vertebrate animals. Their role is to phagocytose (engulf and then digest) cellular debris and pathogens, either as stationary or as mobile cells. They also stimulate lymphocytes and other immune cells to respond to pathogens. They are specialized phagocytic cells that attack foreign substances, infectious Microbes and cancer cells through destruction and ingestion. Macrophages can be identified by specific expression of a number of proteins including CD14, CD11b, F4/80 (mice)/EMR1 (human), Lysozyme M, MAC-1/MAC-3 and CD68 by flow cytometry or immunohistochemical staining. They move by action of Amoeboid movement.

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SPECIFICATIONS

Catalog Number

DCABY-783

Hosts

Mouse

Reactivities

Hum, Rat, Bov, Goat, Horse, Rabbit

Clone

NBD498

Target

Macrophages

Isotype

IgG1

Clonality

Monoclonal

Storage Temp

Store at +4В°C. DO NOT FREEZE.This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.