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Anti-MARCH1 monoclonal antibody, clone MAAG6019

Anti-MARCH1 monoclonal antibody, clone MAAG6019

Cat no: CABT-BL2321

Supplier: Creative Diagnostics
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Mouse Anti-Human MARCH1 monoclonal antibody for ELISA. MARCH1 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH1 downregulates the surface expression of major histocompatibility complex (MHC) class II molecules (see MIM 142880) and other glycoproteins by directing them to the late endosomal/lysosomal compartment (Bartee et al., 2004 [PubMed 14722266]; Thibodeau et al., 2008 [PubMed 18389477]; De Gassart et al., 2008 [PubMed 18305173]).[supplied by OMIM, Mar 2010]
Catalogue number: CABT-BL2321
Reactivities: Human
Hosts: Mouse
Applications: ELISA
Conjugates: Unconjugated
Clone: MAAG6019
Gene: 55016
Target: MARCH1
Isotype: IgG2a
Clonality: Monoclonal
Storage temp: Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°Cin small aliquots to prevent freeze-thaw cycles.

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