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Anti-MCM10 polyclonal antibody

Cat no: CABT-BL5128

Anti-MCM10 polyclonal antibody

Rabbit Anti-Human MCM10 polyclonal antibody for IP, WB. The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre-RC) and it may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein can interact with MCM2 and MCM6, as well as with the origin recognition protein ORC2. It is regulated by proteolysis and phosphorylation in a cell cycle-dependent manner. Studies of a similar protein in Xenopus suggest that the chromatin binding of this protein at the onset of DNA replication is after pre-RC assembly and before origin unwinding. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008]

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SPECIFICATIONS

Catalog Number

CABT-BL5128

Hosts

Rabbit

Reactivities

Hum

Conjugates

Unconj

Target

MCM10

Gene Id

55388

Isotype

IgG

Clonality

Polyclonal

Storage Temp

Store at 4В°C.

SUPPLIER INFO

Creative Diagnostics

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