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Anti-MHC Class II monoclonal antibody, clone UES42.2 [APC]

Anti-MHC Class II monoclonal antibody, clone UES42.2 [APC]

Cat no: DMAB27527

Supplier: Creative Diagnostics
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Mouse anti-Human MHC Class II monoclonal antibody for FC, WB, IHC. MHC (major histocompatibility complex) Class II molecules are found only on antigen-presenting cells. The peptides presented by class II molecules are derived from extracellular proteins (not cytosolic as in class I); hence, the MHC class II-dependent pathway of antigen presentation is called the endocytic or exogenous pathway. Loading of class II molecules must still occur inside the cell; extracellular proteins are endocytosed, digested in lysosomes, and bound by the class II MHC molecule prior to the molecule"s migration to the plasma membrane.
Catalogue number: DMAB27527
Reactivities: Human
Hosts: Mouse
Clone: UES42.2
Gene: 3115
Target: HLA-DPB1
Isotype: IgG1
Clonality: Monoclonal
Storage temp: -20°C. Avoid freeze/thaw

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