Anti-MRSA monoclonal antibody, clone BD21

Mouse anti-MRSA monoclonal antibody for ELISA, ICC/IF. Methicillin-resistantStaphylococcus aureus, MRSA bacterium also be referred to asmultiply-resistant Staphylococcus aureus or oxacillin-resistantStaphylococcus aureus, ORSA, evolved the ability to survive treatment withbeta-lactam antibiotics, including penicillin, methicillin, andcephalosporins. Common strains of MRSA are EMRSA15 and EMRSA16.EMRSA16 isbest described epidemiologically & found to be identical to theST36:USA200 strain. Under the new international typing system, ST36:USA200strain is now called MRSA252. It is not entirely certain why this strain hasbecome so successful, whereas previous strains have failed to persist. Oneexplanation is the characteristic pattern of antibiotic susceptibility. Boththe EMRSA15 and EMRSA16 strains are resistant to erythromycinandciprofloxacin. It is known that Staphylococcus aureus can surviveintracellularly, and these are precisely the antibiotics that best penetrateintracellularly; it may be that these strains of S. aureus are therefore ableto exploit an intracellular niche. Most cases of CA-MRSA are caused by a CC8strain designated ST8:USA300, which carries mec type IV, Panton-Valentineleukocidin, PSM-alpha and enterotoxins Q and K,and ST8:USA400. Othercommunity-associated strains of MRSA are ST8:USA500 and ST59:USA1000.

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