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Anti-MSH6 (Internal) polyclonal antibody, clone D2D3

Cat no: CABT-B739

Anti-MSH6 (Internal) polyclonal antibody, clone D2D3

Rabbit Anti-Human MSH6 polyclonal antibody for EMSA, ICC/IF, IHC-P, IP, WB. This gene encodes a protein similar to the MutS protein. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides, prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein of this gene combines with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene have been identified in individuals with hereditary nonpolyposis colon cancer (HNPCC) and endometrial cancer.

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SPECIFICATIONS

Catalog Number

CABT-B739

Hosts

Rabbit

Reactivities

Hum, Mouse

Conjugates

Unconj

Clone

D2D3

Target

MSH6

Isotype

IgG

Clonality

polyclonal

Storage Temp

Keep as concentrated solution. Aliquot and store at -20В°C or below. Avoid multiple freeze-thaw cycles.

SUPPLIER INFO

Creative Diagnostics

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