Rabbit Anti-MX1 monoclonal antibody for WB, IP. MX1 (Myxovirus resistance protein 1/MxA) is an interferon-inducible antiviral protein that confers resistance to RNA viruses. MX1 has GTPase activity, and GTP-bound MX1 adopts a conformation that enables interaction with viral nucleocapsids. This interaction blocks transport of viral nucleocapsids to the nucleus, which prevents transcription of the viral genome. Structural studies suggest that the antiviral activity of MX1 involves the formation of MX1 oligomeric rings around viral nucleocapsids.