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Anti-MYOM1 (internal region) polyclonal antibody

Cat no: CABT-BL2561

Anti-MYOM1 (internal region) polyclonal antibody

Rabbit Anti-Human MYOM1 polyclonal antibody for IHC, ELISA. The giant protein titin, together with its associated proteins, interconnects the major structure of sarcomeres, the M bands and Z discs. The C-terminal end of the titin string extends into the M line, where it binds tightly to M-band constituents of apparent molecular masses of 190 kD (myomesin 1) and 165 kD (myomesin 2). This protein, myomesin 1, like myomesin 2, titin, and other myofibrillar proteins contains structural modules with strong homology to either fibronectin type III (motif I) or immunoglobulin C2 (motif II) domains. Myomesin 1 and myomesin 2 each have a unique N-terminal region followed by 12 modules of motif I or motif II, in the arrangement II-II-I-I-I-I-I-II-II-II-II-II. The two proteins share 50% sequence identity in this repeat-containing region. The head structure formed by these 2 proteins on one end of the titin string extends into the center of the M band. The integrating structure of the sarcomere arises from muscle-specific members of the superfamily of immunoglobulin-like proteins. Alternatively spliced transcript variants encoding different isoforms have been identified.

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SPECIFICATIONS

Catalog Number

CABT-BL2561

Applications

ELISA

Hosts

Rabbit

Reactivities

Hum

Conjugates

Unconj

Target

MYOM1

Gene Id

8736

Clonality

Polyclonal

Storage Temp

Store at -20В°C. Aliquot to avoid repeated freezing and thawing.

SUPPLIER INFO

Creative Diagnostics

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