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Anti-Norketamine Monoclonal antibody, clone NBC0020

Cat no: DMAB27408


Supplier: Creative Diagnostics
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Sheep anti-Norketamine monoclonal antibody for ELISA, WB, Dot, IHC, IA. Ketamine is absorbable via intravenous, intramuscular, oral, and topical routes due to both its water and lipid solubility.[44] When administered orally, Ketamine undergoes first-pass metabolism, where it is biotransformed in the liver by CYP3A4 (major), CYP2B6 (minor), and CYP2C9 (minor) iso-enzymes into norketamine (through N-demethylation) and finally dehydronorketamine.[45] Intermediate in the biotransformation of norketamine into dehydronorketamine is the hydroxylation of norketamine into 5-hydroxynorketamine by CYP2B6 and CYP2A6. Dehydronorketamine, followed by norketamine, is the most prevalent metabolite detected in urine.
Catalogue number: DMAB27408
Hosts: Sheep
Applications: ELISA
Conjugates: Unconjugated
Clone: NBC0020
Target: Norketamine
Clonality: Monoclonal
Storage temp: +2-+8°C

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