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Anti-Optineurin polyclonal antibody

Cat no: CABT-BL6315

Anti-Optineurin polyclonal antibody

Sheep Anti-Human Optineurin polyclonal antibody for IP. This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]

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SPECIFICATIONS

Catalog Number

CABT-BL6315

Hosts

Sheep

Reactivities

Hum

Target

OPTN

Gene Id

10133

Isotype

IgG

Clonality

polyclonal

Storage Temp

12 months at -20?C; aliquot as required

SUPPLIER INFO

Creative Diagnostics

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