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Anti-Orexin A (aa 14-33) polyclonal antibody

Anti-Orexin A (aa 14-33) polyclonal antibody

Cat no: DPAB3845

Supplier: Creative Diagnostics
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Rabbit anti-Bovine Orexin A (aa 14-33) polyclonal antibody for IHC. Orexin A (hypocretin 1) a 33 amino acid peptide and orexin B (hypocretin 2), a 28 amino acid peptide, are both derived from a common 130 amino acid precursor, prepro orexin. Orexin A and Orexin B stimulate food consumption when administered intracerebroventricularly to rats. Orexin gene expression in the brain is highly restricted to distinct populations of neurons located in specific hypothalamic regions, including the lateral hypothalamic area (LHA), a region implicated in feeding behaviour. Orexin A and orexin B bind to and activate two closely related G protein coupled receptors (GPCRs), termed Orexin 1 (OX1) and Orexin 2 (OX2) receptors. Dysfunction of the orexin peptide system has been linked to narcolepsy.
Catalogue number: DPAB3845
Reactivities: Bovine
Hosts: Rabbit
Conjugates: Unconjugated
Gene: 3060
Target: Hcrt
Clonality: Polyclonal
Storage temp: After reconstitution keep aliquots at -20ºC for a higher stability, and at 4ºC with an appropriate antibacterial agent. Glycerol (1:1) may be added for an additional stability. Avoid repetitive freeze/thaw cycles.

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