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Anti-Orexin A (aa 14-33) polyclonal antibody

Cat no: DPAB3845

Anti-Orexin A (aa 14-33) polyclonal antibody

Rabbit anti-Bovine Orexin A (aa 14-33) polyclonal antibody for IHC. Orexin A (hypocretin 1) a 33 amino acid peptide and orexin B (hypocretin 2), a 28 amino acid peptide, are both derived from a common 130 amino acid precursor, prepro orexin. Orexin A and Orexin B stimulate food consumption when administered intracerebroventricularly to rats. Orexin gene expression in the brain is highly restricted to distinct populations of neurons located in specific hypothalamic regions, including the lateral hypothalamic area (LHA), a region implicated in feeding behaviour. Orexin A and orexin B bind to and activate two closely related G protein coupled receptors (GPCRs), termed Orexin 1 (OX1) and Orexin 2 (OX2) receptors. Dysfunction of the orexin peptide system has been linked to narcolepsy.

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SPECIFICATIONS

Catalog Number

DPAB3845

Hosts

Rabbit

Reactivities

Bov

Conjugates

Unconj

Target

Hcrt

Gene Id

3060

Clonality

Polyclonal

Storage Temp

After reconstitution keep aliquots at -20ºC for a higher stability, and at 4ºC with an appropriate antibacterial agent. Glycerol (1:1) may be added for an additional stability. Avoid repetitive freeze/thaw cycles.

SUPPLIER INFO

Creative Diagnostics

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