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Anti-P. gingivalis Monoclonal antibody

Cat no: DMAB9448


Supplier: Creative Diagnostics
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Mouse Anti-P. gingivalis Monoclonal antibody for WB, AP. Porphyromonas gingivalis belongs to the phylum Bacteroidetes and is a non-motile, gram-negative, rod-shaped, anaerobic pathogenic bacterium. It forms black colonies on blood agar. It is found in the oral cavity, where it is implicated in certain forms of periodontal disease, as well as the upper gastrointestinal tract, respiratory tract, and in the colon. Collagen degradation that is observed in chronic periodontal disease results in part from the collagenase enzymes of this species. In patients harbouring Porphyromonas gingivalis one finds high levels of specific antibody in the serum. Additionally Porphyromonas gingivalis has been linked to rheumatoid arthritis. Porphyromonas gingivalis contains the PAD (Peptidyl-Arginine Deaminase) which is involved in citrullination. Patients with Rheumatoid Arthritis have an increased incidence of periodontal disease and antibodies to the bacterium are significantly more common in patients with Rheumatoid Arthritis.
Catalogue number: DMAB9448
Hosts: Mouse
Conjugates: Unconjugated
Target: P. gingivalis
Isotype: IgG1
Clonality: Monoclonal
Storage temp: -20 °C, Avoid freeze / thaw cycles

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