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Anti-PDE6A polyclonal antibody

Anti-PDE6A polyclonal antibody

Cat no: CABT-BL2869

Supplier: Creative Diagnostics
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Rabbit Anti-Human PDE6A polyclonal antibody for IHC. This gene encodes the cyclic-GMP (cGMP)-specific phosphodiesterase 6A alpha subunit, expressed in cells of the retinal rod outer segment. The phosphodiesterase 6 holoenzyme is a heterotrimer composed of an alpha, beta, and two gamma subunits. cGMP is an important regulator of rod cell membrane current, and its dynamic concentration is established by phosphodiesterase 6A cGMP hydrolysis and guanylate cyclase cGMP synthesis. The protein is a subunit of a key phototransduction enzyme and participates in processes of transmission and amplification of the visual signal. Mutations in this gene have been identified as one cause of autosomal recessive retinitis pigmentosa. [provided by RefSeq, Jul 2008]
Catalogue number: CABT-BL2869
Reactivities: Human
Hosts: Rabbit
Conjugates: Unconjugated
Gene: 5145
Target: PDE6A
Clonality: Polyclonal
Storage temp: Store at 4°C. For long term storage store at -80°C. Aliquot to avoid repeated freezing and thawing.

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